Tianeptine sulfate dosage reddit Withdrawal from Sulfate is also much easier than sodium in my experience. Moderate discomfort but manageable. So no worries with responsible use. There was literally no information on dosing for this type of tianeptine, so I’m starting a thread to discuss it. Was lethargic and anxious but think it was just because I wasn't getting high anymore Day2: took 11 grams sulfate. I received 2g tianeptine sulfate powder today from Ceretropic. To prepare, I purchased green bali kratom powder, 3 packages of immodium tabs, and cold & flu medicine all on a friend’s recommendation. 5-25 mg at once, 3x a day) (low withdrawal risk) . I was taking tianeptine sulfate during the 3 days leading up to withdrawal. Tianeptine abuse can I'm currently taking 25 mg twice each day. . 5 and then 50mg. Or check it out in the app stores &nbsp; &nbsp; TOPICS. from what I gather, a recreational dose for t. I learned after 12. The whole point of using the sulfate is to get the benefits of tianeptine without the short half life of and high peak plasma levels of the sodium. 1900 100mg sulphate On Saturday and Sunday I decided to take Tianeptine Sulfate Experience Hello friends, I've recently had the pleasure of experiencing the effects of tianeptine sulfate. 5mg. Day 1 Sunday: 10 gram sulfate. Internet Culture (Viral) Amazing I've always felt an effect from 12. In your example, I would feel the initial 100mg, wait say 30 mins, then take the other 100mg And I wouldn't feel anything above a standard 100mg dose feeling. I am curious about using tianeptine sulfate for depression, anxiety, fatigue and motivation. 5mg doses. 5 mg and I am planning to take it 3 times a day but I am not sure how many hours before the next dose, taking second dose 4 hours after first dose and third dose 4 hours after 3rd dose ? or there should be like 7+ hours between each dose ? It is not prescribed so I am self medicating for some personal reason I’d wanted to quit for months, and this forced me. I could never take more than 100mg/day without becoming a zombie and needing a nap. i’ve read some people say dose of the sulfate has to be like 200-400 mg for a good high but idk. ), but my psychiatrist said that some people feel the effect at lower doses. I know if I even do a 75 mg dose for two consecutive days, I won't feel a baseline normal mood. This morning I increased the dose to 20mg in the empty capsule, but still Hi, I'm new to nootropics so forgive me if this question seems basic. I am taking 25mg of sulfate which is equal to 12,5mg sodium. Lately, I've been stacking Memantine to reduce tolerance, now I'm back to about 15-20mg doses about 2-3 times a day, happy with it. I don't find any benefits from splitting the doses. Or check it out in the app stores I have been taking 25 mgs of Tianeptine sulfate once or twice a day for the past 18 months. Tried a new variant of Tianeptine called Ethyl Tianeptine i, claimed as being six times more potent than normal Tianeptine. Sulfate is somewhere around 40% less effective as sodium so you need a larger dose, however, it has a longer half life so you do not need as many doses. All in all I’m a big fan of this form. How much would be a good dosage? Lethal dose or ld50 is a term used to describe the amount needed to kill somebody relative to kilogram by milligram, also that's very interesting but then again it could just be that it's sulfate, try the sodium next time and tell me how you feel, for sulfate won't give you any of the good old opiate effects, rather more stronger antidepressant Reddit iOS Reddit Android Reddit Premium About Reddit Advertise Blog Careers Press. Kratom is about 1 billion times easier to manage and get off of in my opinion. 5mg of Sodium = 40mg of Sulfate. the problem i experienced using kratom and tianeptine sulfate at the same time is that i would forget to dose one or the other Tianeptine sulfate is a dosage-dependent mood booster for me if taken during the day, and the cure for a lifetime of nightmares if taken just before bed. bio and found their products effective for tapering purposes. Or 3/4 sodium and 1/4 Sulfate then over days bring it down to mostly Sulfate. I then wanted to know what happened if i upped the dose and did like 100 mgs at once Didn't feel much. Subtle, but I'd imagine the drawback to be more pronounced given your proposed dosage. I’m curious about whether it has an opioid ‘feel’ to it. The third dose depends on if I need to go out, etc - sometimes I don't take a third dose of sulfate and just take 10-20mg tianeptine sodium because it doesn't last as long (sulfate can mess with my sleep). any thoughts? I also suspect people are dosing improperly, taking large doses 1-2x per day rather than following the model of human studies that use lower doses (<500mg) 6x a day, roughly every 2 hours. Does that mean Sodium is more potent as suphate at the same mg dose? Your dosage seems like suphate is longer lasting or maybe it just has like a slower Release effect on people. I would normally take 20-30mg per dose, about 3-4 times a day, by the last dose I was gonzo. The other took 2800 mg in four doses throughout the day. Or check it out in the app stores Working on a taper down, right now I'm at 80mg free acid (same dose I used for sulfate when I had it) Reply reply Similar to Tianeptine sulfate, Tianeptine free acid is stable and easy to store and handle relative to Tianeptine sodium. If you’re disciplined enough to taper, then try to get lower than 1g/day. However you do you, if you decide to do it recreationally I recommend 180 to 200 milligrams of it if you have Tianeptine Sodium and are opioid naive, if you have Tianeptine Sulfate the dosage will be different. Be aware that Sulfate absorbs much slower than Sodium. I've been working my way off sodium with sulfate, and then will move dosages down from As we all know, the pharmacokinetics of tianeptine sulfate haven't been published except for in a controlled release form. I started out with the recommended 12. So figure 1:3(ish). Last week I received 10 grams of the Sulfate forum and from what I read, it is easier for dosing, less hygroscopic and has longer lasting effects, but after trying this everyday for a week I think it is much more then that. I was told me that it was the same as Ethyl Tianeptine i, so i pulled the trigger and bought some. Looking at the powder, I am realizing what a tiny amount a daily dose of approximately 12. During that time I intentionally stopped taking it two times for a period of 5 days each time as I wanted to see if there was a problem with cessation and i didnt read all the posts so idk if this has been said but those boxs are tianeptine sulfate ( aka extended release ) zaza / pegasis / tianna are all sodium ( instant release ) sodium is stronger then sulfate gram for gram idk the exact ration but In humans, a single dose of tianeptine (12. I average 4-5 doses a day. The Sulfate seems much more stable, with the Sodium there would be a come-up, a peak and a comedown. Both subjects reported that their time between tianeptine sulfate doses (varying 100 -200 mg) immediately lengthened by 15-30%, as the agmatine was clearly increasing the systemic duration and efficacy of 84. I also understand that sulfate is Get the Reddit app Scan this QR code to download the app now. When it goes out, I just buy another of the same scale - they last a while. I'd say in general, it takes about 20-40 minutes to kick in. Hope this helps. I was wondering what difference I’ll notice from just taking the sulfate. Boy was this a true statement. sulfate? however some sources claim that ~100mg sulfate is enough. Get the Reddit app Scan this QR code to download the app now Dosage: Sodium=15-25mgx2 OR Sulfate=30-50mgx1, I set exact dosage according to my feelings at that moment Reply reply Tianeptine sodium ain't got shit on tianeptine sulfate. anyone know a good dose? i took around 100+ mg and its like whatever. Tianeptine sodium was also a dosage dependent mood booster, but it I took around 200mg tramadol 4 times per day and reduced my Tianeptine dose from ~700mg to ~300mg over the course of a month, still taking it about 10-12 times a day. 5mg dose. I tried the sulfate for a couple of weeks and didn't notice much, the sodium maybe provided some small lift after trying it for a month but I was getting more benefit from my MAOI and dropped it. Splitting the doses up in both cases generally, help to offer consistent effects of the drug throughout the day. I have the least experience with FA which I was Cheapest price on Ebay right now for 5 grams Tianeptine is $35 + $13. I recommend starting at 40mg and staying if it's comfortable. I put it in an empty capsule. I've bought some along with my first order of Sodium to avoid dosing 3 times a day and have tried various dosages from 25mg to 75mg/day either at once or twice a day and the only effects I got from the Sulfate form were a mild opioid-like roll with the higher doses. After 2 weeks! 1g of Longvida, wait 30min, 1g of Agamantine wait ~1hr before sublingual tianeptine. I’ve used both. solutions. I took 50mg of tianeptine sulfate this morning, feeling pretty good right but now I am just left wondering how many times I can take this stuff on a Get the Reddit app Scan this QR code to download the app now Tianeptine has sort of a ceiling effect like kratom as in the effects just plateau after a certain dose. I tried the sulfate before trying the sodium, because I wasn't interested in the highs & lows and also redosing 3x a day. Sodium seems to be the strongest/shortest, sulfate is a little less intense but longer lasting, ethyl ester sulfate seems to be more longer lasting than normal sulfate, idk about the free amino acid version If yes, what dosage do you think it would be closer to a 150-200mg dose of Tramadol when no tolerance present ? From what I've read, therapeutically dosage of Sulphate is 25-40mg once a day, and I'm wondering if a dose of 80mg to 120mg once a day only per needed basis would be a similar experience. I would suggest taking just one 25mg dose for at least a week, preferably 2 weeks, before determining if you want to try a second 25 mg dose (or like I did at first, half a capsule for a second dose). Just a brief comment to tell about my experience with Sulfate. Thanks Occasional use (you said once a weekj), you won't have withdrawals or build tolerance. With the sulfate I now dose around 60mg in the morning and another 40mg 4 hours later - that way I All at once. very easy to get. I took tianeptine sulfate during a panic attack once and then I suddenly started calming down very quickly about 15-20 minutes after taking it. So I’m conclusion: Tianeptine is fine in normal doses daily (12. I have medically grade Tianeptine sodium from German Pharmacys. Three times per day. Selective u-opioid agonist typically induce euphoria, which may contribute to its antidepressant effect ( source Wikipedia) Mitragyna speciosa ( Kratom) Mitragynine acts primarily via u-opioid receptor, though it's oxidation production Mitragynine pseudoindoxyl, acts more First off I have to explain tolerance so that people don't take doses similar to me. Good luck! Get the Reddit app Scan this QR code to download the app now. At that dose (or any starting dose), the body will adapt and If used at 12. Tianeptine (Stablon) Discussion & Experiences I'm taking a similar dose but I find that its starting to be inconsistent in its effects. The only interesting thing I notice from this form but not sooo much in regular sulfate is a bit more of a stimulant effect, which I am Tianeptine Sulfate and Tianeptine Sodium. In order to get off sodium, I would start doing your normal doses but splitting it half and half with sodium and Sulfate. Or check it out in the app stores (from 3+gpd) as well as taking large doses of Kratom to help with the WDs but it didn't seem to work well at all. I felt very talkative and full of energy. If you are taking KRATOM for the first I believe with the correct dosage and ROA, tianeptine does provide some the focus, anxiety relief and confidence in my work that opiates that drew me to other opiates If used at 12. Because Ethyl Tianeptine i is extremely rare, I was sorta forced to try Tianeptine Ethyl Ester Sulfate. However, I do find it easier to dose therapeutically with sulfate, as the rise and subsequent fall of the tianeptine in your system is less dramatic and thus provides a "smoother" effect. I'm by no means an expert with this substance and there are people on the sub-reddit with vastly more expertise than myself, hopefully they will chime in. 5gpd to 1. 12,5mg for 3x times a day is the therapeutic dose for depression which DOESN'T cause addiciton or So, I bought 2 gs of tianeptine sulfate powder from noot depot. 50 shipping for sodium form (sulfate form is more expensive). Day 1 - Tianeptine Sulfate, though pricier, offers a smoother tapering process due to its extended effects. Agmatine has a short half life and this needs to be taken into consideration for dosing schedules. --- Generic Name: Tianeptine sulfate Brand Names: Coaxil, Neluptin, Stablon, Salymbra among others. 5 mgs three times a day. 5gpd Tianeptine sulfate is often taken at a dosage rate of 25mg per day taken in 1 or 2 times daily. Sodium being usually the one that’s abused as it hits hard but lasts not long, whereas sulfate lasts decently long but takes a bit to kick in and likewise isn’t quite as strong since it’s lasting longer. I mistakenly thought 12. Duration, absorption, potency. The bottle just lists the ingredients as follows: Combretum Quadrangular leaf, Tianeptine, piper methsticum, gelatin, purified water. After a couple days building up to a 40mg dose of tianeptine sulfate (x1/day) I then started to research things that are safe to take with these two that can help more with athletic performance and after some research, I decided to add Phenylpiracetam (60mg) to the stack while lowering tianeptine sulfate dose to 60mg as well Either you are dosing at absolutely insane levels or just buying from very expensive sources. I’ve just done that, myself at around that amount. Therapeutic Category: Antidepressant, tricyclic CAS: 0066981-73-5 Chemical Formula: C21H25ClN2O4S Using an oral syringe its good to rinse out with at least 30 ml of water before and then several hours after plugging 3-absorbed materials cannot be removed from the body, but plugging does cause a build up and a but of a time release, so rinsing again with your syringe when you want the absorption to cease is a viable option as well. Based on the graph of effects, it looks like one daily dose of 41mg (3. I haven’t had trouble getting off 100mg/day of sulfate several times now over the years. Tianeptine sodium is dosed at 12. At that dose (or any starting dose), the body will adapt and quickly achieve homeostasis which naturally leads to upping the dose in order for it to remain effective. Imodium is just the brand name for anti-diarrheal medicine. The two different forms. The sulfate is much forgiving in his regard, and single doses of 50-60mg, spread out, shouldn’t lead to rebound anxiety or adddoction/tolerance. It tends to cause a more sleepy and comfortable state as opposed to the rushing stimulant effect from the sodium form. That's 150mg but it varies slightly since I am measuring the powder and Is there any sort of consensus as to what would be an appropriate therapeutic dose range with tianeptine sulfate? I've read that 25mg is a good starting point for minimal If you were to dose 7mg of sulphate every 5 hours 3 times a day, when you wake up the second day your blood tianeptine would be around 3mg, rising to 10mg after your first dose, lowering My suggestion is to simply start off taking low doses and if you determine you need more then take more in roughly 30 minute increments. Honestly, I've found that both of these tools have a time and place to be used. 1900 100mg sulphate Sunday: 1300 100mg sulphate. Sometimes you need a short, strong dose of pain-free energy which, in our case, calls for 40 mg of sodium. so did another 50 like 2 hours later I tried tianeptine sodium at 12. I first started with 30 mgs, and it was nice, had a solid mood boost for like 5 hours and had no noticeable come down. 5mg), I've put together some ideas for thought about taking a guess at the pharmacokinetics. 5mg of tianeptine sodium, and I've experimented with doses of tianeptine sulphate from 20mg-60mg, but I've never been able to actually "feel" it. 1630 25mg sulphate On Wednesday, Thursday and Friday I found the effects very stimulating - almost like low dose MDMA. Or check it out in the app stores tianeptine sulfate dose and experiences . Or check it out in the app stores Tianeptine sodium Vs Sulfate . The effect is "subtle", one shouldn't feel like they took something. I'm addicted to the tianeptine class of drugs at 1. Do not take more than 50 mg of tianeptine sodium in a single day. I was very productive. Personally, I've had positive experiences with tianeptine from rcd. 5mg sodium = 40mg sulfate. 12. Get the Reddit app Scan this QR code to download the app now Tianeptine is great, I first got the sodium and then switched to sulfate. 5 mg per ml. Stage 2 - 3. At the recommended dosage of around 10-15 mg I noticed immediate antidepressant effects. Nothing happened to calm me down, and I was confused about how calm I suddenly became then I realized it was probably the tianeptine, lol. At this dose my cognitive function did not feel impaired nor did I Tianeptine Warning. I am currently taking 130mg 4-5x per day which is very high, but it has no effect at lower doses. Reply reply I picked up some Tianeptine sulfate from nootropics depot. It seems to have a longer duration all around. I see zero reason to use the I personally stayed at that dose for 3 weeks before going up to 37. I stick to the lower end of dosing, and take days off. I take one 50 mg dose of tianeptine sulfate every morning (at the same time as my first d-amph dose). It's been life-changing to shed my fear of sleep. Start on the lower end of the spectrum and adjust from there. Advertisement Hello, I recently got a bottle of 25 mg Tianeptine Sulphate tablets and was wondering what a good starter dose of it is? I am looking to utilize this substance to help with depression and other issues of that sort. Im sure in time you will find out that Im giving you the best option. I’ve seen mixed information on whether the therapeutic effects at standard doses are due to opioid activity or some affect on glutamate. I have a lot experience with the sodium. 5mg, 3x a day as well as tianeptine sulfate 25mg/50mg once a day. We never re-dose or use tia two days in a row or more than twice a week. I was steady at roughly this dose for the last 8 months, then started tapering in earnest a month ago from that point. That's how I'm likely gonna measure unless enough people call me a Now the sulfate I dose at about 3'xs the sodium, per the links on Reddit, but I only take it once per day. "The standard dosage of Agmatine Sulphate for NO effects are 250mg, however for opiate tolerance reduction – effective dosages range from 500mg to 2000mg" That spreadsheet is on the quitting tianeptine sub. 5-2g SD 2-2. The last few times, I just stopped taking it one day and was recently received 2 grams of tianeptine sulfate. Make drastic cuts immediately as the lower you go the more difficult shaving any mgs off becomes. I tapered down from 1g per day of sodium with sulfate so there is some opioid activity at 80mg+, I chose to jump from 300mg of sulfate per day 2 days ago and it has the exact same withdrawals of sodium. Kratom has a ceiling effect that really does not allow one to get super duper high, tianeptine allows one to get super, duper, duper high, and it builds tolerance and physical withdrawal effects much, much faster and these withdrawals are much, much, much more theres plenty of information about dosing and everything youre asking already existing in previous posts, theres an entire subreddit for tianeptine, theres psychonaut wikipedia with suggested doses. The difference between the two forms of Tianeptine you mentioned are efficacy and half life. But I didn't experience anything. Sodium is definitely stronger mg for mg. Saturday: 1300 25mg sulphate. The sulfate does seem to last longer and have a gradual come up and down, I would dose 20mg 2x a day (sometimes 40mg 1x a day). If you’re going to abuse tianeptine in high doses, occasional (one dose every several weeks or months) is fine (low withdrawal risk) If abusing tianeptine daily in higher than normal amounts, even if it’s not that much more (maybe 50-100+ mg?), then withdrawal will 1130 25mg sulphate. Anyways, I find 80mg a day works for me. I am not a recreational user of tianeptine, I use it in therapeutic doses (in the past just used 25mg of the sulfate once a day) and have found it to be really helpful for depression in ways that nothing else has. Maybe a little withdrawal first thing in the morning that quickly resolved with dosing (2hours) Day 3: 13 grams sulfate. 5g SF and 3-5g a day levels. 5 mg) results in ~ 1 μM maximal concentration of the drug in the plasma What does this mean? A 12. That isn’t a low dose of sulfate, but I would say you should be okay with that overall and could easily taper over a week or two if needed. Tolerance builds quite fast. 5mg/3 Stablon doses, it might be a useful and effective drug, but I can't visualize this happening. You need to quit tianeptine right know and switch to diazepam, suboxone, methadone or at least some morphine and tapper. Most of the time it works wonderfully but other times it has very little effects and just seems to make me sleepy. The tianeptine stopped working at 30mg and I began to increase the dose, each time it stopped working, I would increase the dose. Looking for a opiate-like experience with a great deal of euphoria. I usually dose 20-25mg in the morning, and 30mg before lunch. 5mg dose (the recommended dose) will result an in vivo concentration sufficient for the activation of MOR (EC50 ~ 0. Some people also say 25 mgs of sulphate is the suggested daily dose. It is said to be mildly water soluble but other solubility information is not available. You need to take atleast 400mg to feel anything and you would only get addicted to it if you took that high of a dose everyday. The suggested prescription antidepressant dosage of sodium is 12. 5mg x3 sodium = 40mg sulfate. I have been taking 40mg 2x a day with good effects. Please do your research before you comment. I find it extremely hard to believe you did any research at all I've seen it said a few times around the interwebs, that approx. I have a milligram scale ordered that should arrive this week. If possible, it was taken with, or shortly after the tianeptine sulfate dose. In an effort to ensure I'm taking a proper therapeutic dose of tianeptine sulfate (equivalent to tianeptine sodium 12. 3x regular dose) Tianeptine Sulfate would get you the same peak blood plasma concentration as the Sodium version (~430 ng/ml), however, it would last much longer, with significant Some people say 25 mgs of suplhate is the same as 12. Longer come up, peak, residual effects. The standard and max dose is three times a day, 1-1-1-0 (for people with normal liver and kidney function. So I can be 100% that it is clean. It requires using more at each dose but the effects aren't as fleeting as with the sodium. I'll be the devil's advocate Buy Longvida Optimized Curcumin or Curowhite and doable dose (reverse tolerance) for min 2wks. sulfate, so does that equate to 300-400mg of t. I noticed that using tianeptine sulfate may not be as simple as I thought. Maybe it would be slightly prolonged, but it wouldn't just add on top of the initial dose. Don't be a pussy either. Several hours later I mixed it in some water to see if that would produce results, still nothing. sodium is ~100mg, and is between 3-4 times more potent than t. Get the Reddit app Scan this QR code to download the app now. Basically double reccomended dose, and had intended to max out at 40mgx3 or 60mgx2= 120mg a day to match what I mistakenly thought was the therapeutic dose. 4-it can Sulfate can be just as recreational as sodium. Its I take it in half-doses spread 4x throughout the day (the d-amph). At other times we enjoy about 6 hours of bliss with 100 mg of sulfate. Same feelings. Seems the dose is equal to 60 mg Tianeptine Sulfate as well so that is a plus. I just took 212 mg of the free amnio acid version feel amazing never tried the fa version but it's in-between the sodium and sulfate and 212 mg is a a good dosage for me in my opioin. Taste and structure indistinguishable from the sulphate version. don't want to do sodium version bc too short-lived, but with the sulfate the guidelines is too scarce. I’m desperately wanting to quit and I have Suboxone. Not nearly as anxious and actually sedated by end of the day Stick to under 100mg, you will find a excuse to dose higher than that though. Also since I have never done it before any advice would be much appreciated, thanks! Posted by u/bconaughty - 1 vote and 15 comments I have Tianeptine Sodium 12. You don't want to develop dependence to this shit, it will Been on and off both several times. The sulfate form from Ceretropic is longer lasting with smoother effects. No one will tell you the dose And some doses of prescription only tianeptine also works very mild one day and next day hits much stronger. 5 of sodium. 2–1 μM) but not DOR. The sulfate is useless to get high. Two weeks ago, I started dosing Tianeptine Sulphate in an attempt to improve my mood and lower my anxiety, which most likely was at a point where it could be considered a disorder clinically. I have the same question, I think the sulphate dosage will have to be a little bit higher but Has anyone successfully tapered off Tianeptine with Tianeptine Sulfate ? The question I have is I have aquired meds over the last few weeks and have Gabapentin 800mg (20+) I have Subutex 4mg (3 pills) I have Xanax 1mg (25 or so) I also have lots of clonidine and Lucemyra which is a “new” drug used for opiate withdrawal similar to clonidine. If affordability allows, tianeptine Sulfate could be a worthwhile option. But it is much more useful for depression, anxiety, and is a very noticeable nootropic when you keep it in the mg double digits. iame53 The WD process will increase slightly with sulphate. Also whenever I combined tianeptine sulfate with dexamp the effects from both just sort of canceled each other out but It depends on if you have tianeptine sodium or the I know tianeptine sodium is MUCH more abuseable and induces MUCH more euphoria and at lower doses than the tianeptine sulfate and I understand the precise pharmacological and physiological mechanisms for this. Even a dose of 100 mg tianeptine sulfate once a day for 5 consecutive days would lead to some form of rebound depression. Tianeptine is a full agonist at the u-opioid and O-opioid receptors with negligible effects at the k-opioid receptors. It’s also easier to taper as you don’t get as much of the sudden warm/good feelings that sodium brings. 5mg x 3 = 38mg would be, and even smaller if you took the 12. How can that be? Would not 25 mgs be a fraction of the suggested daily dose? I've read some people dose 40 or 50 mgs a Soluble only in KOH, NaOH, sodium bicarbonate etc. Look for “tianeptine,” “tianeptine sodium” or “tianeptine sulfate” listed in the ingredients or supplement facts. Does anyone know if the Tianeptine pills called Pegasus have sodium or sulfate in them? I recently switched to them from the Zaza bc they seemed to last longer. I like the effects a lot but noticed it's more stimulating than higher doses (which increase mood more and provide a more calming I've seen realistic measurements of therapeutic doses in proportion to pennies as far as weight and size. And it comes in both powder and pill form. Sodium is the most recreational one, this version is mainly for people looking for a strong opiate We use both tianeptine sodium and sulfate. This was mostly copied pasted from an article, for therapeutic dosing. So I really like this new form of tianeptine. cxnjk kaebk oeim ips fzrvq bmxf ndwg hxw kjmi ipqsk